Read what our clients have to say about us
On the Olis™ DSM CD
"The sun is shinning in Holland, MI, and the power supply and ignitor have arrived, and the CD is working. Yeah! ...My team and I are very happy and now we will push the instrument to maximum usage... :-) Folks, instruments will always have problems but having service like what y'all have provided is not as common. Thanks very much for your prompt action ...Best, Moses”
Moses Lee, Dean of Natural and Applied Sciences, Hope College
“Gorgeous data!”
Catherine Murphy, University of South Carolina, owner of an
Olis™ DSM 17 CD
“No calibration did it for
me.”
Marc Pusey, NASA Flight Center, on what first appealed to him
about dual beam CD
“The [Olis DSM 1000 CD] machine
is really good...the performance of the instrument is usually
not appreciated by the average users, because they don't realize
the difficulty of measuring small CD signals and because they
don't have experience with other instruments.”
Wim Jiskoot, University of Utrecht
“After 2000 hours of use,
our Olis [DSM 1000 CD] needs a new lamp.”
Timothy Deming, UCSB
“We're loving the instrument.”
Paul M. Horowitz1,
University of Texas Health Science Center
“With signal averaging, we
were able to obtain what I think are data that no one has previously
reported...direct evidence of transition from random coil to alpha
helix in the presence of increasing dioleoyl phosphotidylserine
concentration in vesicles. The data are spectacular.”
Thomas
P. Sakmar, M.D., Rockefeller University
“In their bid the vendor claimed,
There is no experimentally justifiable reason to have dual beam
CD. To which I replied that it was like saying there was no reason
to have two lenses in a pair of glasses or a dual beam spectrophotometer.”
John V. Schloss, Kuwait
University
“The single scan that was
baseline corrected looked every bit as good as the average of
5 scans that was baseline corrected, which is what I sent you.
I was following the handiwork of a competitor and he did 5 scans
and averaged them. I was trying to stay pretty close to what he
did. In hind sight, that was unnecessary after I have looked at
the traces and compared them. Needless to say, the results were
very reproducible but you already know that.”
Michael Sehorn, LSUMC Shreveport
“We are having a good time
with our CD. It is performing well and we are learning a lot from
playing with just one protein and a tryptophane- minus mutant
of the same. We are teasing out some subtle biphasic responses
in ellipticity as a result of temperature change which may correlate
with biphasic behavior in the redox potential of our protein.”
Marcia Holden, NIST
"[[We are] running CPL/FDCD measurements in solution, thin films and the results obtained are very good. With the information obtained we have a better understanding of the properties necessary in synthesising chiral compounds and their interaction with solvents and other matrices. We are very happy with the Olis unit, a very versatile piece of research equipment.
Anton Launikonis, CSIRO Australia, Owner of Olis DSM 17 plus Polarization Toolblx and RFL
On the Olis™ RSM
1000
“You have created a marvel
of simplicity, functionality, and versatility, all in one.”
Brian G. Fox, UWisc
“First though, let me say
that we're putting the RSM through its paces, and so far it's
been giving us nice results all across the board. I've now obtained
data for reactions occurring on microsecond, millisecond and minute
scales, and I even had to follow one reaction for 2 h! I'm hoping
to get some data on my enzyme of interest pretty soon, and as
soon as I do I'll send you guys a copy.”
Andy Pacheco, UW Milwaukee
“One of the reviewers said
there is no way that you can do optical stopped-flow studies with
a B12 compound, yet there it is, because unlike a diode array,
you are not blasting the hell out of the sample with white light
in the RSM.”
George Reed of U Wisc after obtaining spectra on a B12 compound
(Biochemistry, 2000)
“Even a single protein's complexity
requires multiple wavelength analysis.”
Celia Bonaventura, Duke Marine Lab
“My department can afford
the best of only one kind of spectrophotometer and the RSM is
it for me.”
Thomas D. Bolden, Alcorn State University, owner of two Olis™
RSM 1000s
“My students and postdocs
were extremely impressed with the instrument and are, in fact,
now lobbying me to purchase the hardware needed to run fluorescence
experiments rather than purchase a fluorimeter from another vendor
(...the original plan).”
Stephen O. Smith, SUNY Stony Brook
“Another thing that we have
learned is that you can really do some cool things using the RSM
to monitor an argon laser being tuned through its different spectral
lines. You twiddle the monochromator, and one peak disappears,
and the next line starts to increase...great activity to demonstrate
how the laser works for undergraduate.”
Lawrence E. Welch,
Knox College
“Once you see all the additional
information which the spectra give you, you would never give it
up...any other means of doing stopped-flow is primitive.”
Robert Byrne, USF Medical School
“The machine is remarkably
simple in design and powerful in concept.”
Donald A. Bryant, PSU
“With the OLIS RSM, even in
a simple case, where the data are AgB, you get so much more information
in the same amount of time, why not do it to get the one rate?
And with more complicated processes, you will see things with
multiple wavelengths that you cannot with fixed wavelength. And
even if you have enough sample to do different wavelength shots,
it takes too long and you have to assume that all mixtures are
the same, which they almost can't be.”
Daniel Kim-Shapiro, Wake Forest University
“What we enjoy most is the
simplicity of use. We do not use the instrument continually, yet
can easily crank it up to do as many runs as needed in a short
time. I would definitely recommend OLIS to my colleagues.”
Dr. Paul F. Cook, UON
“You have indeed proved to
my satisfaction that the instrument and software are as you describe
in your literature and work as expected...you have now made all
of us with standard type stopped-flows dissatisfied with what
was 'state of the art.'”
Lawrence
J. Parkhurst, UNL
“Clearly, you have assembled
an excellent tool that should be a key component of our work for
years to come.”
A. Grant Mauk, UBC
“The optics of the Olis RSM
has no competition from other optic systems in its superior performance.
It is easy to service with only one moving part and is especially
useful for the light sensitive samples when compared with the
diode-array reverse optics.”
Ah-lim Tsai, UTH-TMC
“It is wonderful! The RSM
acquires data in seconds that I formerly took in hours [and] the
RSM software does the job in a matter of seconds!”
H. James Harmon, OKU
“The present data, obtained
in the RSM instrument from OLIS has significantly improved signal/noise
compared to the data obtained in the [diode array] instrument.”
Robert
S. Phillips, UGA (Biochemistry, 1996)
“You have a lot of people
down here loving the instrument.”
Clifford Unkefer, Los Alamos National Laboratory
“To anyone looking at low
light level chemiluminescent or bioluminescent reactions, or wishing
to obtain spectral and kinetic data on transient or precious biological
samples the rapid scanner is a must. A wonderful instrument!!”
Dr. Russel Hart, SeaLite Sciences, Inc.
“I am continually amazed at
the capabilities of the instrument...It is very exciting to gain
new insight so quickly.”
Charles B. Grissom,
University of Utah
“...even the brief training
my postdocs received on the Olis has allowed us to become quite
comfortable in its operation. We have been using it as though
it has always been in the lab.”
Dr. Paul F. Cook, University of Oklahoma
“I am more than satisfied
with the performance of the machine and its versatility.”
Dr. Denise A. Mills, Michigan State University
On the Olis™ Upgrades
“[The Cary 14]...instrument
has been the workhorse of the lab...”
Thomas Owens, Cornell University, in an email 12 years after
Olis modernization
“You know, it has been 20
years on that machine - wow! I don't have any instrument in my
lab that has survived for that length of time.”
Dr. Paul Hoffman, Dalhousie University, on the endurance of
his upgraded Cary 14
“I had a Cary 14 done...I
have been very happy with it! We subsequently got an Aminco DW2
done by OLIS a couple of years later...The 14 with the update
is really a nice machine & we do all our UV work with this...My
people have been happy.”
P. Frederick
Guengerich, Vanderbilt University
“Every person I talked to
had nothing but praise for the Olis upgrade [of the Cary spectrophotometers].”
Kevin Schum, CVI Laser
“The [Olis modernized Aminco
DW2] spectrophotometer has been working perfectly ever since [modernization
was done]. It is fair to say that I do share the opinion of my
students and colleagues about your system, it is excellent!!!
We have been using routinely the instrument in the scanning mode
and it is performing flawlessly.”
Roberto Iglesias Prieto, UNAM, Cancun
“We have used the OLIS USA
stopped flow and modified [SLM-Aminco] SPF-500 for nearly five
years...I am delighted to say that the system has worked flawlessly.
There are probably about a dozen articles based at least in part
on data collected with the instrument. I am a fan!”
Richard E. McCarty, John Hopkins University
“As we expected we are delighted
with the Olis [Aminco] DW2 upgrade.”
Roberto A. Bogomolni, UC Santa Cruz
“We are indeed still using
the updated SLM 4800. It's working well in my hands.”
Gale M. Strasburg, Michigan State University
“I should have done this years
ago!”
Patrick Dansette, University of Rene Descartes, about his modernized
Aminco DW2
“Thanks for your interest
in our experience with modernized Cary 14. It works perfectly
as far as I can tell. I used it in two of my courses to illustrate
the use of the near IR region to measure vibration overtones (of
HCl) and got excellent, nicely resolved spectra. The same was
true for the Vis spectrum of gas phase iodine.”
Dr. Hans van Willigen U Mass Boston
On the Olis™ Service
“[You] did an outstanding
job in the installation and basic training...we have already looked
at peroxynitrite-mediated oxidation of dihrorhodamine with good
results.”
Thomas
P. Sakmar, M.D., Rockefeller University
“No one provides better, more
immediate technical support; and no other company is willing to
change their software (or hardware) for single cases the way Olis
does.”
Dr. Wayne Bolen, UTMB
“Your company probably has
the very best service record of any I have ever dealt with, and
your attention to detail is probably the very best too. It is
an honor knowing you guys and a special treat having you as friends.”
Jim Mahaney, Virginia University School of Medicine
“First, let me emphasize that
we have been extremely happy with the quality and speed of the
service and the advice that we have been given by Olis over the
years, and we are absolutely confident that we shall continue
to feel the same way in the future.”
Joseph Michl, University of Colorado
“I just wanted to let you
know, I installed the new power supply you sent and the Olis DW2
is now working perfectly! Thank you very much for your help!!
The service we received from you and your company was without
a doubt the best service we have had from any company we have
dealt with.”
Trevor Swartz, UC Santa Cruz
“The files are fine and the
OLIS conversion-Cary 14 runs as always - perfect. Thanks for your
help.”
Geoffrey F. Strouse, UCSB
“The TAs haven.t asked me
for help except in the very beginning. My conclusions are that
the Windows system is excellent for this application. We haven't
had to ask for anything from you guys. I haven't gotten a chance
to use the spectrometer in more sophisticated apps, so I can't
speak to this, but I am anxious to get around to working with
the spec myself. You have happy customers here. Tell Paul Boxrud
hello, it was great meeting him.”
Dr. Helen Richter, U Akron
“You can go ahead and use
my last email which is basically the highest praise the tech-support
in any company can get. I have never seen an instrument getting
fixed within 24 h including diagnosis of the problem and sending
the replacement part.”
Kai H. Griebenow,
University of Puerto Rico
“I love the instrument; I
love the people.”
William van Antwerp, Minimed Technologies
Footnotes
1)
After a long battle with a type of blood cancer, Professor Paul
Horowitz died June 27, 2005. Dr. Markandeswar Panda, a colleague
of 15 years standing, is now the owner of this Olis DSM 17 CD
at UTHSC San Antonio.